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High-purity Buy 3-FPM reagent General

Buy 3-FPM

Purity Level ≥ 99.8% High-Purity Grade (Ready to Use)
Category Group General
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Variation Price: €3000.00

Premium scientific reagent synthesized under strict laboratory conditions.

Scientific Characterization & Product Details

3-Fluorophenmetrazine (3-FPM, PAL-593) is a morpholine-based stimulant created by introducing a single fluorine atom into position 3 of the once-approved appetite suppressant phenmetrazine.It has been circulating on the premium compound market since 2014 as a gray area alternative to classic amphetamines.
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ChemistryrnThe compound is the 3-fluoro-regioisomer of phenmetrazine;The fluorinated variants 2-FPM and 4-FPM only differ in the position of the fluorine on the phenyl ring.Morpholine ring and N-ethyl group remain unchanged compared to the starting molecule.
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Pharmacologyrn3-FPM acts as a selective catecholamine releaser: it triggers carrier-mediated outward transport of dopamine (EC₅₀ 43 nM) and norepinephrine (EC₅₀ 30nM), while serotonin is hardly affected (EC₅₀ 2.6 µM).In HEK293 cells, it inhibits DAT and NET with cocaine-like potency (IC₅₀ < 2.5 µM), but leaves SERT almost unaffected (IC₅₀ > 80 µM).At higher concentrations, the transporters reverse their direction and transport cytosolic monoamines into the synaptic cleft.
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MetabolismrnIn vitro with human hepatocytes shows that the molecule rapidly undergoes N-oxidation, aryl-hydroxylation with subsequent O-methylation, side chain hydroxylation and cleavage of the ethyl bridge is broken down;This creates, among other things,the bis-dealkylated core fragment.These metabolites are then glucuronidated or sulfated and excreted renally.

Customer Reviews

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Frequently Asked Questions

What is the purity level of Buy 3-FPM?

Our Buy 3-FPM is supplied with a guaranteed purity level of at least 99.8%. Every batch undergoes rigorous validation to verify chemical integrity before dispatch. It is ready to use.

Do you sell to individuals?

Yes, we sell to both individuals and businesses. All our products are ready to use.

How are orders packaged and shipped?

Orders are shipped globally using discreet, vacuum-sealed packaging with full end-to-end tracking. Shipments are packed in neutral, heavy-duty parcels to ensure complete privacy and security.

How should Buy 3-FPM be stored?

Store in a cool, dry place at room temperature (15–25 °C), shielded from direct sunlight and excess humidity. Sealed in its original vacuum packaging, chemical stability is preserved for at least 24 months.